Hotels in Isla Santa María

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Where to stay in Isla Santa María?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Isla Santa María

Learn more about Isla Santa María

Isla Santa María is well-known for its attractions such as Galápagos National Park and Post Office Bay.

Frequently asked questions

What accommodations do travelers recommend in Isla Santa María?
Guests like Floreana Lava Lodge.
Can I book refundable hotels in Isla Santa María?
If you’re looking for the flexibility to change your plans to Isla Santa María, most properties provide refundable* rates you can book. You can find these properties by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in Isla Santa María be like during my trip?
With an average temperature of 72°F, Isla Santa María is a great place if you want to enjoy the sunshine year all year long.
Why should I book my Isla Santa María hotel through Hotels.com?
There are plenty of reasons to book your Isla Santa María travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Find out more about Isla Santa María

Find out more about Isla Santa María

If you're looking to discover somewhere new, look no further than Isla Santa María. Whether you're planning to stay for a night or for the week, the area around Isla Santa María has accommodations to fit every need. Search for hotels in Isla Santa María with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Isla Santa María hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Isla Santa María hotel deals are here with our lowest price guarantee.