What a lovely place to stay!
We thoroughly enjoyed our time in Kampot and our stay at Mea Culpa. The location is very nice - it's a short 10 minute walk from the "center" of town so you are close to everything but not so close that there will be a lot of noise in the evenings. You're also very close to the waterfront and the evening sunset boast cruises.
The rooms were spacious and comfortable. Our only room complaint was that the wifi wasn't great, but not a big deal overall. The power went out very briefly a few times but this seems to be very common in Kampot.
We had breakfast every morning at the hotel which was so tasty and very reasonably priced compared to your options in town. I recommend the fresh fruit salad - best $2 spent!
There are free bikes you can borrow as needed which was appreciated to get around town. If you need to go further (to the pepper plantations, Kep, etc) then the staff can help arrange a tuk tuk for you.
The staff were all SO kind and helpful!
If you're going to Kampot, definitely stay here!