Hotels in Santa Cruz de la Sierra

your current months are December, 2024 and January, 2025.
December 2024
January 2025

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Where to stay in Santa Cruz de la Sierra?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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One Key™ members save 30%+ on select hotels until December 4 with our Black Friday deals. Stay by December 15, 2025.

Frequently asked questions

What hotels do travelers recommend in Santa Cruz de la Sierra?
Guests like Rural house (full rental) El Olivar del Marqués for 26 people, Risco Chico rural suite and The House of Luis for 4 people.
Can I book refundable hotels in Santa Cruz de la Sierra?
If you need the flexibility to change your plans to Santa Cruz de la Sierra, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in Santa Cruz de la Sierra be like during my trip?
July and August are typically the warmest months in Santa Cruz de la Sierra when the average temp is 77°F. January and February are the coldest months when the average temperature is 47°F. October and December are the months with the most rain.
Why should I book my Santa Cruz de la Sierra hotel through Hotels.com?
There are lots of reasons to book your Santa Cruz de la Sierra trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.