Hotels in San Cosme y Damian

your current months are February, 2025 and March, 2025.
February 2025
March 2025
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Where to stay in San Cosme y Damian?

On a rooftop patio

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Top landmarks in San Cosme y Damian

Learn more about San Cosme y Damian

San Cosme y Damian is well-known for its attractions such as Buenaventura Suarez Planetarium and Guarani Jesuit Ruins of San Cosme and San Damián.

Frequently asked questions

Can I book a refundable hotel in San Cosme y Damian?
If you’re looking for the flexibility to change your plans to San Cosme y Damian, most hotels offer refundable* bookable rates. You can see these properties by searching our site and using the “fully refundable” filter to narrow down the results.
What will the weather in San Cosme y Damian be like during my trip?
January and February are typically the warmest months in San Cosme y Damian when the average temp is 80°F. July and June are the coldest months when the average temperature is 62°F. October and November are the months with the most rain.
Why should I book my San Cosme y Damian hotel with Hotels.com?
There are plenty of reasons to book your San Cosme y Damian travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.