Hotels in Santa Cruz de la Sierra

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Where to stay in Santa Cruz de la Sierra?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santa Cruz de la Sierra

The region around Santa Cruz de la Sierra is home to attractions such as Juan Pizarro de Orellana Palace and City Walls.

Frequently asked questions

What hotels do travelers recommend in Santa Cruz de la Sierra?
Can I book refundable hotels in Santa Cruz de la Sierra?
If you need the flexibility to change your plans to Santa Cruz de la Sierra, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in Santa Cruz de la Sierra be like during my trip?
July and August are typically the warmest months in Santa Cruz de la Sierra when the average temp is 77°F. January and February are the coldest months when the average temperature is 47°F. October and December are the months with the most rain.
Why should I book my Santa Cruz de la Sierra hotel through Hotels.com?
There are lots of reasons to book your Santa Cruz de la Sierra trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Find out more about Santa Cruz de la Sierra

Find out more about Santa Cruz de la Sierra

If you're looking to discover somewhere new, look no further than Santa Cruz de la Sierra. Whether you're planning to stay for a night or for the week, the area around Santa Cruz de la Sierra has accommodations to fit every need. Search for hotels in Santa Cruz de la Sierra with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Santa Cruz de la Sierra hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Santa Cruz de la Sierra hotel deals are here with our lowest price guarantee.